Provided herein are methods for detecting and/or confirming the neurogenesis effect of eicosapentaenoic acid utilizing adipose-derived stem cells (ADSCs). Further provided are methods of promoting neurogenesis in ADSCs. Also provided are methods for the use of eicosapentaenoic acid for the production of a neurologic component that may be incorporated into a nutritional composition for promoting neurogenesis in a pediatric subject.