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Immunostimulatory G, U-containing oligoribonucleotides
专利权人:
Zoetis Belgium SA
发明人:
Grayson B. Lipford,Stefan Bauer,Hermann Wagner
申请号:
US14159916
公开号:
US09428536B2
申请日:
2014.01.21
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Compositions and methods relating to immunostimulatory RNA oligomers are provided. The immunostimulatory RNA molecules are believed to represent natural ligands of one or more Toll-like receptors, including Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8). The compositions and methods are useful for stimulating immune activation. Methods useful for screening candidate immunostimulatory compounds are also provided.
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