OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYU "INITIUM-PHARM"
发明人:
LATSERUS, Lyudmila Anatolievna,ЛАЦЕРУС, Людмила Анатольевна,PINIGIN, Anatoly Fedorovich,ПИНИГИН, Анатолий Федорович,MAGANOVA, Faniya Irshatovna,МАГАНОВА, Фания Иршатовна,PINIGINA, Nina Maximovna,ПИНИГ
申请号：
RURU2012/000420
公开号：
WO2013/176564A1
申请日:
2012.05.25
申请国别(地区):
WO
年份:
2013
代理人:
摘要：
A terpenoid agent for the prophylaxis and/or treatment of atherosclerosis and the correction of metabolic syndrome is proposed, as well as the use of the pharmaceutical substance Abisil for the prophylaxis and/or treatment of atherosclerosis and the correction of metabolic syndrome, and the use of the pharmaceutical substance Abisil in preparing a terpenoid agent for the prophylaxis and/or treatment of atherosclerosis and the correction of metabolic syndrome. The proposed terpenoid agent provides an anti-atherosclerotic effect characterized by a decrease in total lipids, total cholesterol, triglycerides, and low-density lipoprotein (LDL) cholesterol in the blood, the stimulation of the secretion with bile of cholesterol and bile acid, a decrease in the level of damage to the aortic intima, and the prevention of the development of arterial calcinosis and the occurrence of myocardial infarction, and also provides, in the case of metabolic syndrome, corrective effects characterized by a normalization of arterial pressure indicators and triglyceride and glucose levels in the blood, and may be used in the case of such diseases as peripheral vascular disease, arterial hypertension, ischemic heart disease, type 2 diabetes mellitus, and a variety of other diseases associated with atherosclerosis, as well as in correcting imbalances in lipid and carbohydrate exchange in the case of metabolic syndrome.Linvention concerne un produit à base de terpénoïdes pour la prophylaxie et/ou le traitement de lathérosclérose et latténuation du syndrome métabolique, lutilisation de la substance pharmaceutique Abicil pour la prophylaxie et/ou le traitement de lathérosclérose et latténuation du syndrome métabolique et lutilisation de la substance pharmaceutique Abicil pour la fabrication dun produit à base de terpénoïdes pour la prophylaxie et/ou le traitement de lathérosclérose et latténuation du syndrome métabolique. Linvention porte sur un produit à base de terpénoïdes qui possède une acti
