THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMT OF HEALTH AND HUMAN SERVICES;UNIVERSITY OF MARYLAND, BALTIMORE
发明人:
THOMPSON, SCOTT,VAN DYKE, ADAM,THOMAS, CRAIG,MORRIS, PATRICK
申请号:
CA3074110
公开号:
CA3074110A1
申请日:
2018.08.28
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to novel alpha5 subunit-selective negative allosteric modulators of GABAA receptors that have been deuterated to improve their medicinal properties by prolonging their half-lives, rendering them useful as fast-acting pharmaceutical treatments for depression related disorders.