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THIENOPYRIDINES AND BENZOTIOPHENES AS IRAK4 INHIBITORS
专利权人:
БРИСТОЛ-МАЕРС СКВИББ КОМПАНИ
发明人:
Ахмад, Салеем,Ли, Лин,Негаш, Лидет А.,Хайнс, Джон,Салеем,Лин,Лидет А.,Джон
申请号:
EA201992674
公开号:
EA201992674A1
申请日:
2018.05.10
申请国别(地区):
EA
年份:
2020
代理人:
摘要:
Disclosed are compounds of Formula (I) or a salt or prodrug thereof, wherein: X is CR4 or N; Y is CR5 or N; provided that only one of X and Y is N; (R1) is: or; wherein R1, R1a, R1b, R1c, R2, and R3 are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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