Rebekah L. Gundry,Kenneth R. Boheler,Erin M. Kropp
申请号：
US16414025
公开号：
US10808222B2
申请日:
2019.05.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are methods of reducing or eliminating undifferentiated pluripotent stem cells, where the methods comprise contacting an effective amount of a compound to a heterogeneous cell population or sample comprising or suspected of comprising differentiated cell types and undifferentiated pluripotent stem cells, whereby the contacting selectively reduces or eliminates undifferentiated pluripotent stem cells from the cell population or sample. Also provided are methods for obtaining a population of stem cell-derived cell types substantially free of undifferentiated pluripotent stem cells as well as isolated populations of such of stem cell-derived cell types.
