INDUSTRY-ACADEMIC COOPERATION FOUNDATION; YONSEI UNIVERSITY
发明人:
Baik Lin SEONG,Yun Ha LEE
申请号:
US15735449
公开号:
US20180177860A1
申请日:
2016.06.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a vaccine composition containing a virus inactivated by a green tea extract, and a preparation method therefor. According to the present invention, when a virus is treated with a green tea extract, there are simultaneous effects of virus inactivation and excellent immunogenicity maintenance, and thus an inactivated vaccine can be prepared by mixing the green tea extract of the present invention and a virus with a proliferative capacity, and infectious diseases caused by the corresponding virus can be effectively prevented since an immune reaction to the corresponding virus is induced when a vaccine composition prepared by the preparation method of the present invention is administered to a subject. In addition, there are advantages of enabling the preparation of a safe virus vaccine since the green tea extract of the present invention is nontoxic, and a preparation process is economical since, unlike a chemical material-based preparation process, a dialysis process is unnecessary.