PROBLEM TO BE SOLVED: To provide a TGR5 agonist using an ingredient that exists in a food and a natural product and has been eaten, a heat production promoter, and an anti-obesity agent.SOLUTION: Ionones that exist also in a natural essential oil are used as an active ingredient of a TGR5 agonist, a heat production medicine, and an anti-obesity agent.COPYRIGHT: (C)2013,JPO&INPIT【課題】食品や天然物中に存在し、食経験のある成分を用いたTGR5作動剤、熱産生促進剤および抗肥満剤を提供すること。【解決手段】天然精油中にも存在するイオノン類をTGR5作動剤、熱産生剤および抗肥満剤の有効成分として利用する。【選択図】なし
