An antifungal and diaper rash treatment creme for cells in skin tissuecomprising anon--medicinal emollient base, an anti-fungal in the emollient base to treatboth obvious fungalinfection as well as nonobvious fungal infection associated with diaper rashand acorticosteroid in the emollient base to immediately reduce irritating symptomsof tissuecongestion, and to thereby substantially accelerate infection disposition inobvious fungustreatment applications by facilitating penetration of less congestedindividual cells in thetissue by the anti-fungal.