Vincent Leonard Cryns,Dmitry Malin,Elena Strekalova
申请号:
US14706086
公开号:
US20160310451A1
申请日:
2015.05.07
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Described herein is TRAIL receptor targeting therapy in combination with metformin for treatment of cancer in humans. Using TRAIL receptor targeting therapy such as the TRAIL molecule, agonistic human monoclonal antibodies against TRAIL receptors, or peptides targeting TRAIL receptors in combination with metformin for the treatment of all types of cancer allows to obtain an optimum therapeutical effect at any time of the progression of the disease.