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Markers for stratification therapy stratification in heart failure
专利权人:
エフ.ホフマン-ラ;アーゲー;ロシュ
发明人:
ディルク ブロック,ハンスペーター ブルンナー,トーマス ディーターレ,ウルズラ-ヘンリーケ ビーンフース-テレン,クリスティアン ツァウッグ,アンドレ ツィーグラー
申请号:
JP2016537268
公开号:
JP6625535B2
申请日:
2014.08.26
申请国别(地区):
JP
年份:
2019
代理人:
摘要:
present invention relates to a method for determining a patient with heart failure are likely to respond to statin-containing therapy. The method, in a sample from a patient, GDF-15 (growth differentiation factor 15), urea, SHBG (sex hormone binding globulin), uric acid, PLGF (placental growth factor), IL-6 (interleukin-6), transferrin, heart troponin, sFlt-1 (soluble fms- like tyrosine kinase-1), prealbumin, ferritin, osteopontin, SST2 (soluble ST 2), and hsCRP least one member selected from (high-sensitivity C- reactive protein) It is based on measuring the level of the marker. Method of predicting the risk of a patient afflicted with death or hospitalization, are further contemplated, wherein the patient has undergone and statin-containing therapy have heart failure. The method is also based on measurement of at least one level above the markerBACKGROUND
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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