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COMPLEX OF BI-SPECIFIC ANTIBODY AND DIGOXIGENIN CONJUGATED TO A THERAPEUTIC OR DIAGNOSTIC AGENT
专利权人:
发明人:
Ulrich Brinkmann,Rebecca Croasdale,Wilma Dormeyer,Guy Georges,Alexander Haas,Eike Hoffmann,Silke Metz,Olaf Mundigl,Werner Scheuer,Jan Olaf Stracke
申请号:
US14539009
公开号:
US20160009823A1
申请日:
2014.11.12
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to complexes of a) bi-specific antibodies and antibody fragments against a target protein and b) a digoxigenin conjugated to a therapeutic or diagnostic agent, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical compositions containing said antibodies, and uses thereof.
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