A system for treating tissue includes an applicator and a clip assembly. The applicator includes a catheter extending longitudinally and a lumen extending therethrough, a control member extending through the lumen of the catheter. The assembly is releasably coupleable to a distal end of the applicator. The assembly includes a pair of clip arms, proximal ends of which are slidably received within a channel of a capsule, a pair of opposing coupling elements extending proximally from the proximal ends of the arms to be fixed over the distal end of the member so that the arms are movable relative to the capsule via a longitudinal motion of the member between a tissue receiving configuration, in which distal ends of the arms are separated from one another, and a tissue clipping configuration, in which distal ends of the arms are moved toward one another.
