MÉDICAMENT INTERMÉDIAIRE AYANT UNE ACTIVITÉ ANTICANCÉREUSE SYNERGIQUE ET UN MÉDICAMENT ANTICANCÉREUX SYNERGIQUE COUPLÉ AU POLYÉTHYLÈNE GLYCOL, LEUR PROCÉDÉ DE PRÉPARATION ET LEUR UTILISATION
Disclosed are an intermediate drug having synergistic anticancer activity and a polyethylene glycol-coupled synergistic anticancer drug, and a method preparing therefor and use thereof. The intermediate drug has the general structural formula of (I), and the polyethylene glycol-coupled synergistic anticancer drug has the general structural formula of (II). The drugs achieve the combined medication of various anticancer drugs and avoid the toxic reaction caused by the interaction among the drugs or by the pharmacokinetics of the drugs when taking various anticancer drugs, facilitate overcoming the multidrug resistance of cancers, have a synergistic effect, and can be used for preparing anticancer medicaments and for treating cancers.
