ANTI-PD1 ANTIBODIES AND THEIR USE AS THERAPEUTICS AND DIAGNOSTICS

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专利权人:

BEIGENE SWITZERLAND GMBH

发明人:

SONG, JING,LI, KANG,ZHANG, TONG,XU, LANLAN,LIU, QI,PENG, HAO

申请号：

CA3078121

公开号：

CA3078121A1

申请日:

2013.09.13

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

Provided are antibodies that specifically bind to Programmed Death-1 (PD1,Pdcd-1, orCD279) and inhibit PD1-mediated cellular signaling and activities in immunecells, antibodies bindingto a set of amino acid residues required for its ligand binding, and uses ofthese antibodies to treat ordiagnose cancer, infectious diseases or other pathological disorders modulatedby PD1-mediatedfunctions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/