A method for generating a clinical effects map for electrical stimulation using an electrical stimulation lead includes receiving at least one clinical response for stimulation using each of multiple first sets of stimulation parameters where each clinical response is associated with at least one therapeutic effect or side effect. The method also includes determining, using the clinical responses and the first sets of stimulation parameters, a spatial relationship between the electrical stimulation lead and at least one effect region, where each effect region is associated with at least one of the therapeutic effects or side effects； estimating, based on the spatial relationship, at least one clinical response for each of multiple second sets of stimulation parameters； and generating and presenting a clinical effects map illustrating at least the estimated clinical response for one or more of the second sets of stimulation parameters.
