Disclosed are protein kinase inhibitors, compositions comprising such inhibitors, and methods of use thereof. More particularly, disclosed are inhibitors of Aurora A (Aurora-2) protein kinase. Also disclosed are methods of treating diseases associated with protein kinases, especially diseases associated with Aurora-2, such as cancer.Linvention concerne des inhibiteurs de protéines kinases, des compositions comprenant de tels inhibiteurs, et des méthodes dutilisation associées. En particulier, linvention concerne des inhibiteurs de la protéine kinase Aurora A (Aurora-2). Linvention concerne également des méthodes de traitement de maladies associés à des protéines kinases, en particulier des maladies associées à Aurora-2, notamment, le cancer.
