PROTÉINES DE LIAISON MODIFIÉES INHIBANT L'INTERACTION DU RÉCEPTEUR VEGF-A

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专利权人:

Molecular Partners AG

发明人:

申请号：

EP19185024.7

公开号：

EP3593821A1

申请日:

2011.04.29

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention relates to binding proteins specific for VEGF-A, in particular to recombinant binding proteins comprising a polyethylene glycol moiety and a binding domain, which inhibits VEGF-Axxx binding to VEGFR-2. Examples of such recombinant binding proteins are proteins which comprise an ankyrin repeat domain with the desired binding specificity, and a polyethylene glycol moiety. The binding proteins are useful in the treatment of cancer and other pathological conditions, e.g. eye diseases such as age-related macular degeneration.

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中国工程科技知识中心

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http://www.ckcest.cn/home/