VANKAYALAPATI, HARIPRASAD,YERRAMREDDY, VENKATAKRISHNAREDDY,GANGIREDDY, PARAMAREDDY,APPALANENI, RAJENDRA P.
申请号：
CA2932175
公开号：
CA2932175A1
申请日:
2014.04.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to compounds described by Formula: (I) salts thereof, their synthesis, and their use as ITK and JAK3 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and or disorders such disease associated with abnormal cell growth such as autoimmune, inflammation, rheumatoid arthritis, systemic lupus erythematosus, atherosclerosis, ulcerative colitis, psoriatic arthritis, psoriasis, Crohn's, metabolic and cancer diseases. The present invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions and processes for preparing the compounds of the invention.
