BUYSE, MARIE-ANGE,HERMANS, GUY,LINDEMANN, SVEN,GUEHRING, HANS,GUENTHER, RALF,KELLNER, ROLAND
申请号：
CA3063293
公开号：
CA3063293A1
申请日:
2018.06.04
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to immunoglobulins that bind ADAMTS5 and more inparticular to polypeptides, thatcomprise or essentially consist of one or more such immunoglobulins. Theinvention also relates to constructs comprising suchimmunoglobulins, such as immunoglobulin single variable domains (ISVDs) orpolypeptides as well as nucleic acids encoding suchimmunoglobulins or polypeptides； to methods for preparing suchimmunoglobulins, polypeptides and constructs； to host cells expressingor capable of expressing such immunoglobulins or polypeptides； tocompositions, and in particular to pharmaceutical compositions, thatcomprise such immunoglobulins, polypeptides, constructs, nucleic acids and/orhost cells； and to uses of immunoglobulins, polypeptides,constructs, nucleic acids, host cells and/or compositions, in particular forprophylactic and/or therapeutic purposes, such as theprophylactic and/or therapeutic purposes mentioned herein. Other aspects,embodiments, advantages and applications of the inventionwill become clear from the further description herein.
