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Masking orally disintegrating tablet bitterness, and a method of manufacturing the same
专利权人:
キッセイ薬品工業株式会社
发明人:
三村和樹,武田泰浩,金田健
申请号:
JP2013067740
公开号:
JP5693635B2
申请日:
2013.03.28
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
The present invention provides an orally disintegrating tablet containing mitiglinide calcium hydrate. The tablet has reduced bitterness and quickly disintegrates in the mouth, while exhibiting rapid dissolution in the digestive tract. The bitterness-masked orally disintegrating tablet comprises: (a) mitiglinide calcium hydrate; (b) microcrystalline cellulose; (c) at least one masking agent selected from the group consisting of aminoalkyl methacrylate copolymer E, polyvinylacetal diethylaminoacetate, an ethyl acrylate-methyl methacrylate copolymer, and ethyl cellulose; (d) a sugar or a sugar alcohol; and (e) at least one selected from corn starch and partially pregelatinized starch.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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