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INDAZOLE COMPOUNDS AS IRAK4 INHIBITORS
专利权人:
AURIGENE DISCOVERY TECHNOLOGIES LIMITED
发明人:
GUMMADI, VENKATESHWAR RAO,SAMAJDAR, SUSANTA,GUPTA, AJAY
申请号:
SG11201605408R
公开号:
SG11201605408RA
申请日:
2015.01.07
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
The present invention provides indazole compounds of formula (I), which are therapeutically useful as kinase inhibitors, particularly IRAK4 inhibitors, wherein Z1, Z2, R1, R2, R3, ‘m’ and ‘n’ have the meanings given in the specification, and pharmaceutically acceptable salts or stereoisomers thereof that are useful in the treatment and prevention of diseases or disorders, in particular their use in diseases or disorders mediated by kinase enzyme, particularly IRAK4 enzyme. The present invention also provides pharmaceutical compositions comprising at least one of the compounds of the compound of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient.
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