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Amino-quinoxaline and amino-quinoline compounds for use as adenosine A2a receptor antagonists
专利权人:
Joel M. Harris;Bernard R. Neustadt;Hong Liu;Jinsong Hao;Andrew W. Stamford
发明人:
Joel M. Harris,Bernard R. Neustadt,Hong Liu,Jinsong Hao,Andrew W. Stamford
申请号:
US12920928
公开号:
US08415353B2
申请日:
2009.03.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds of the Formula (I), where W represents CH or N; and Q represents —CN, —C(═NOH)NH2, —CONHR1 or various herein described heterocyclic radicals; as well as pharmaceutically acceptable salts, solvates, esters and prodrugs thereof are adenosine A2a receptor antagonists and, therefore, are useful in the treatment of central nervous system diseases, in particular Parkinson's disease.
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