MOON, YOUNG-CHOON,CAO, LIANGXIAN,TAMILARASU, NADARAJAN,QI, HONGYAN,CHOI, SOONGYU,LENNOX, WILLIAM JOSEPH,CORSON, DONALD THOMAS,HWANG, SEONGWOO
申请号:
CA2559408
公开号:
CA2559408C
申请日:
2005.03.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
In accordance with the present invention, compounds that inhibit theexpression of VEGF post-transcriptionally have been identified, and methodsfor their use provided. In one aspect of the invention, compounds useful inthe inhibition of VEGF production, in the inhibition of angiogenesis, and/orin the treatment of cancer, diabetic retinopathy or exudative maculardegeneration are provided. In another aspect of the invention, methods areprovided for the inhibition of VEGF production, the inhibition ofangiogenesis, and/or the treatment of cancer, diabetic retinopathy orexudative macular degeneration using the compounds of the invention.