TAN, Phillip,SIMON, Sandy Alexander,CERVENY, Charles G.,NILSSON, Christy Anne,BRADY, William,LEDBETTER, Jeffrey A.,HAYDEN-LEDBETTER, Martha Susan,THOMPSON, Peter Armstrong,MORALES, Cecile
申请号:
AU2016202696
公开号:
AU2016202696A1
申请日:
2016.04.28
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2016202696A120160526.pdf#####H: ft interwoven NRPortbl DCC FMT l0053907_ .docx-27/04/2016 ABSTRACT The present disclosure provides a humanized anti-CD37 small modular immunopharmaceutical (SMIP) molecule, as well as synergistic combination therapies of CD37-specific binding molecules (such as anti-CD37 SMIP proteins or antibodies) with bifunctional chemotherapeutics (such as bendamustine) that can be administered concurrently or sequentially, for use in treating or preventing B cell related autoimmune, inflammatory, or hyperproliferative diseases.