Brendan M. Crowley,Brian T. Campbell,Joseph L. Duffy,Thomas J. Greshock,Deodial G. Guiadeen,Andrew John Harvey,Belinda C. Huff,Kenneth J. Leavitt,Vanessa L. Rada,John M. Sanders,William D. Shipe,Linda
申请号:
US15463336
公开号:
US09840481B2
申请日:
2017.03.20
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure relates to compounds of formula I that are useful as modulators of α7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation