Navnit H. Shah,Atsawin Thongsukmak,Jaydeep Vaghashiya,Dipen Desai,Wantanee Phuapradit
申请号:
US15001960
公开号:
US10034865B2
申请日:
2016.01.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are pharmaceutical compositions, e.g., in the form of tablets, containing a therapeutically effective amount of an HIV protease inhibitor, e.g., ritonavir, a pharmaceutically acceptable aqueous-soluble polymer, and an erosion-enhancing agent having a particle size distribution in the range of about 1 μm to about 350 μm, wherein the composition is substantially free or free of surfactant. Methods of making the compositions, and methods of using them to treat HIV infection are also provided.