JOSEFINA SANTOS MURILLO,MARIA ELENA GARCÍA ARMENTA,VICTOR GUILLERMO ÁLVAREZ OCHOA
申请号：
BRPI0816264
公开号：
BRPI0816264A2
申请日:
2008.09.05
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The invention relates to a pharmaceutical composition comprising the synergic combination of three agents with venotonic and vasoprotective activity, known as a purified, micronized flavonoid fraction of diosmin and hesperidin and calcium dobesilate, as well as pharmaceutically acceptable excipients, which are formulated in a single dosage unit to be orally administered. The composition, which is used to control and treat chronic venous insufficiency, provides improved therapeutic effect and faster pharmacological action in less time, with smaller concentrations of the active principles and a reduction in the risk of severe complications and/or side effects.
