RADBOUD UNIVERSITAIR MEDISCH CENTRUM;TROPIQ HEALTH SCIENCES B.V.;PANSYNT B.V.
发明人:
HERMKENS, PEDRO HAROLD HAN,SCHALKWIJK, JOSEPHUS,JANSEN, PATRICK ANTONIUS MARTINUS,BOTMAN, PETER
申请号:
CA2966848
公开号:
CA2966848A1
申请日:
2015.11.06
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention concerns novel pantothenamide analogues of formula (I), having antimicrobial activity. In particular, the pantothenamide analogues of the present invention are not sensitive to pantetheinase activity. The pantothenamide analogues of the present invention thus, for the first time, are suitable for use in therapeutic and or prophylactic treatment of microbial infection in a human or animal subject in need thereof, in particular in the treatment of protozoal infections. (Formula (I))