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COMPRIME CONTENANT DU DELTA 9-TETRAHYDROCANNABINOL, PROCEDE DE FABRICATION ASSOCIE ET UTILISATION DE CE COMPRIME POUR UN TRAITEMENT ORAL
专利权人:
ECHO PHARMACEUTICALS B.V.
发明人:
DE VRIES, JAN ALBERT,FERNANDEZ CID, MARIA VANESA,HEREDIA LOPEZ, ANA MARIA,EIROA MARTINEZ, CRISTINA MARIA
申请号:
CA2929325
公开号:
CA2929325A1
申请日:
2014.10.29
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention relates to compressed tablets for peroral deliveryof the cannabinoid ?9-tetrahydrocannabinol(THC).More particularly, the invention provides a compressed tablet having a tablet weight of 25-1000 mg, said tablet being composed of: compressed tablet containing delta 9-tetrahydrocannabinol, method for its manufacture and use of such tablet in oral treatment · 30-90 wt % of a granulate; · 10-70 wt % of lactose; and · 0-30wt % of other tablet excipients; wherein the granulate contains: a.2-5 wt % of ?9-tetrahydrocannabinol; b.2-20 wt % of sucrose fatty acid mono-ester; c.50-96 wt % of lactose; dØ05-0.6 wt % of antioxidant; and e.0-25wt % of other granulate excipients. The compressed tablets according to the invention can conveniently be used in the treatment of spasticity and pain caused by multiple sclerosis, neurophatic pain, chronic pain, behavioral disturbance by Alzheimer's disease, stroke, spinal cord injury, peripheral neuropathy, neurogenic pain, nociceptive pain and nausea. The invention further provides a method for the manufacture of the compressed tablets.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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