The present invention provides a aqueous patch that contains the ketoprofen, not only improving the work efficiency of manufacturing but also offering excellent stabiling of preservation and the percutaneous absorption of the ketoprofen.A ketoprofen lysine salt containing aqueous patch consists of the support and the adhesive layer accumulated on the support, which is characterized in that the adhesive preparation doesnt contain the glycerin, and the ketoprofen lysine salt as a principal agent is dissolved completely in the polyethylene glycol of the mean molecular weight 1000 or less, wherein polyethylene glycols of 1000 or less are one or two and more selected from a group consisting of polyethylene glycol 200, polyethylene glycol 400, polyethylene glycol 600, and polyethylene glycol 1000.本發明提供一種水性貼附劑,其為含有凱妥普洛芬之水性貼附劑,不但改善製造作業效率,且凱妥普洛芬之保存安定性及經皮吸收性優異。一種具備支持體和積層於支持體之黏著劑(膏體)層之貼附劑,其特徵為於不含有甘油而混合平均分子量1000以下之聚乙二醇之膏體中,將主藥成分凱妥普洛芬離胺酸鹽以完全溶解之狀態混合之含有凱妥普洛芬離胺酸鹽之水性貼附劑,平均分子量1000以下之聚乙二醇為由聚乙二醇200、聚乙二醇400、聚乙二醇600及聚乙二醇1000而成之群選擇之1種或2種以上之聚乙二醇之含有凱妥普洛芬離胺酸鹽之水性貼附劑。
