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Paneled capsule shells for release of pharmaceutical compositions
专利权人:
Stephen Mark McAllister
发明人:
Stephen Mark McAllister
申请号:
US12285843
公开号:
US08454992B2
申请日:
2008.10.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Capsule shells for use in multi-part dosage forms have generally cylindrical shell members with a snap fit component on an interior surface adjacent an open end, for connection to a linker part of the dosage form. The shell member also has a plurality of spaced apart integrally formed thin (relative to circumferentially adjacent shell member portions) panels located adjacent a closed shell member end, for preferential dissolution and release of pharmaceutical compositions from the shell member interior. The ratio of the thickness of the panels to the thickness of the shell member ranges from about 0.2 to about 0.6. The panels can be integrally formed together with the shell member as reliefs or depressions on the inner surface of the shell member by injection molding, and panel thicknesses as thin as about 0.1 mm can be achieved.
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