新規なピュリニルピリジニルアミノ－２，４－ジフルオロフェニルスルホンアミド誘導体、その薬学的に許容可能な塩、その製造方法及びそれを有効成分として含むＲａｆキナーゼの阻害活性を有する薬学的組成物

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专利权人:

株式會社メドパクト

发明人:

シム ウンキョン,キム ナムドゥ,シム テボ,キム スンヨン

申请号：

JP2013541920

公开号：

JP5689182B2

申请日:

2011.11.25

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

A novel purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative, a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition with an inhibitory activity against Raf kinase, containing the same as an active ingredient are provided. The purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative of the present invention effectively regulates the activity of B-Raf kinase, and thus may be useful for preventing or treating cancers induced by the over-activation of Raf kinase, especially various melanoma, colorectal cancer, prostate cancer, thyroid cancer, ovarian cancer and the like.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/