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专利权人:
NAVIPHARM. CO.; LTD.*
发明人:
CHANG-KYOO, LEE,SANG-GEUN, PARK
申请号:
MX2013000001
公开号:
MX2013000001A
申请日:
2011.07.05
申请国别(地区):
MX
年份:
2013
代理人:
摘要:
The present invention relates to a time-delayed sustained release pharmaceutical composition for oral administration, which comprises an immediate release phase and a prolonged sustained release phase, wherein said immediate release phase and prolonged sustained release phase respectively comprise dapoxetine therein as an active ingredient. The pharmaceutical composition of the present invention comprises dapoxetine, which is an agent for treating premature ejaculation, in both the immediate release phase and the prolonged sustained release phase thereof, to thereby immediately exhibit the effectiveness of the pharmaceutical composition of the present invention in order to enable a patient to achieve sexual satisfaction during the early stage of administration, as well as to reduce side effects by means of the time-delayed sustained release of the prolonged sustained release phase during the early stage of administration and enable a continuous in vivo absorption of dapoxetines, to thereby lengthen the duration of the effectiveness of the pharmaceutical composition of the present invention. Further, agents for treating erectile dysfunction, such as sildenafil, tadalifil or the like can be added to the immediate release phase so as to allow for a coincidence of the durations of the effectiveness of a premature ejaculation treatment agent and erectile dysfunction treatment agents, even though a half-life difference exists between the two types of treatment agents, thus maximizing patient satisfaction.La presente invención se relaciona con una composición farmacéutica de liberación prolongada y acción retardada para la administración oral, la cual comprende una fase de liberación inmediata y una fase de liberación sostenida prolongada, donde la fase de liberación inmediata y la fase de liberación sostenida prolongada comprenden respectivamente Dapoxetina en ellas como un ingrediente activo. La composición farmacéutica de la presente invención comprende Dapoxetina, la c
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