DIRECTIONAL TARGETING OF DISTANT BCL11A CONTROLS FOR FETAL HEMOGLOBIN REINUCTION

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专利权人:

The Children's Medical Center Corporation

发明人:

ORKIN, Stuart H.,BAUER, Daniel E.,XU, Jian

申请号：

DK13858006

公开号：

DK2925864T3

申请日:

2013.11.27

申请国别(地区):

DK

年份:

2019

代理人:

摘要：

Provided herein are methods and compositions for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level. Also provided herein are methods and compositions relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/