Preparation method of a compound Agent derived from 5 - fluoro - 1H - pirazolopiridina; intermediaries that participate in the same compound and the final Compound Crystal forms is obtained, which is useful in the treatment of cardiocirculatory disturbances.
The present application relates to a novel and efficient process for preparing novel substituted 5-fluoro-1H-pyrazolopyridines of the formula (VI) which are suitable as an intermediate for production of medicaments and for production of medicaments for treatment and/or prophylaxis of cardiovascular disorders. More particularly, the 5-fluoro-1H-pyrazolopyridines of the formula (VI) are suitable for preparation of the compound of the formula (I) which serves for production of medicaments, for production of medicaments for treatment and/or prophylaxis of cardiovascular disorders.<;p>;La presente invenció;n se refiere a un procedimiento de preparació;n de un compuesto de fó;rmula (VI) que se prepara a partir del compuesto de la fó;rmula (V) haciendo reaccionar este compuesto con sulfolano y acetonitrilo con una posterior deshidratació;n del compuesto (V) para dar nitrito (VI), un procedimiento para preparar el compuesto de fó;rmula (I), su forma cristalina I, un procedimiento de preparació;n de la forma cristalina I; una composició;n farmacé;utica que lo comprende, y el uso del mismo en el tratamiento de trastornos cardiociculatorios.<;/p>;