REUTELINGSPERGER, CHRISTIAAN, PETER, MARIA,MOONEN, PETER, JOZEF, JACOBUS,VERMAIRE, ADRIAAN, THOMAS
申请号:
NZ59686210
公开号:
NZ596862A
申请日:
2010.06.03
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
596862 METHOD FOR ENHANCING PHAGOCYTOSIS OF PHOSPHATIDYLSERINE-EXPOSING CELLS Provided is an Annexin A5 variant, comprising at least one and not more than twenty RGD sequences within the Annexin chain. The RGD sequences can be separated by 1-3 amino acids selected from A, G, I, L, M, P, S, T and V and can be cyclically linked. The compounds are useful in stimulation phagocytosis of cells that expose phosphatidylserine on their surface.