Lucilla Del Gaudio;Roberto Tassinari;Alessandra Belloni;Rossella Bortolo;Thomas Paul Lockhart
发明人:
Lucilla Del Gaudio,Thomas Paul Lockhart,Alessandra Belloni,Rossella Bortolo,Roberto Tassinari
申请号:
US13845515
公开号:
US09884299B2
申请日:
2013.03.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Process for the preparation of a water-in-oil or oil-in-water nanoemulsion wherein the dispersed phase is distributed in the dispersing phase in the form of droplets having a diameter ranging from 1 to 500 nm, comprising:1) the preparation of a homogeneous water/oil blend (I) characterized by an interface tension lower than 1 mN/m, comprising water in an amount of 30 to 70% by weight, at least two surface-active agents having a different HLB, selected from non-ionic, anionic, polymeric surface-active agents, said surface-active agents being present in such a quantity as to make the blend homogeneous;2) the dilution of the blend (I) in a dispersing phase consisting of oil or water with the addition of a surface-active agent, selected from non-ionic, anionic, polymeric surface-active agents, the quantity of the dispersing phase and surface-active agent being such as to obtain a nanoemulsion having a HLB different from that of the blend (I).