Internalizing human monoclonal antibodies targeting prostate cancer cells in situ

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专利权人:

The Regents of the University of California

发明人:

Bin Liu,James D. Marks

申请号：

US15418588

公开号：

US10479839B2

申请日:

2017.01.27

申请国别(地区):

US

年份:

2019

代理人:

摘要：

This invention provides a method that allows selection of antibodies against cells (e.g., tumor cells) in situ using laser capture microdissection. By restricting antibody selection to binders of internalizing epitopes, a panel of phage antibodies was generated that targets clinically represented prostate cancer antigens.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/