A nerve interface device comprises at least one cuff portion 5, 7； and a first pair of electrodes, 15, 17 mounted on the cuff portion, wherein the cuff portion forms at least part of a passageway for receiving a nerve 13 along a cuff axis 19 passing through the passageway, and wherein the electrodes are spaced apart in the direction of the cuff axis 19. The device may be used in a nerve stimulation system, using a stimulation device to generate an electrical signal. The device may further form part of an implantable system for stimulating and/or monitoring activity of a nerve. The implantable system may be used in a method of modulating activity, or in a method of stimulating and monitoring activity of a nerve. A second pair of electrodes may be mounted on the cuff portion in a ring, concentric to the first pair of electrodes. A physiological sensor and comparison module may also be provided to detect physiological activity and the relationship between the electrical signals and physiological activity. Detection may be performed using EIT.L'invention concerne un dispositif d'interface nerveuse (1, 3) comprenant : au moins une partie manchon； et une première paire d'électrodes (15, 17) montées sur la ou les partie(s) manchon (5, 7). La partie manchon (5, 7) comporte une position assemblée, dans laquelle elle (5, 7) forme au moins une partie d'un passage destiné à recevoir un nerf (13) le long d'un axe de manchon (19) traversant le passage. Les électrodes de la première paire (15, 17) sont espacées l'une de l'autre dans la direction de l'axe du manchon.
