It refers to an inflatable mattress (10) connectable with an inflation and deflation system and adapted to lift a patient in the therapy for treatment of bedsores. The mattress comprises:- a first series of inflatable cells (44)- a second series of inflatable cells (48)- at least one feed tube (12) to be connected with the inflation and deflation system- a first manifold (16), connected with the first series of cells (44) and the at least one feed tube (12).The first series of cells (44) and the second series of cells (48) are arranged next to each other on forming together an only structure having a first side edge and a second side edge. The first manifold (16) is positioned along the first side edge.