Mark E. HAYES,Charles O. NOBLE,Francis C. SZOKA, JR.
申请号:
US15413362
公开号:
US20170128366A1
申请日:
2017.01.23
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides liposomes loaded with chelating agents, pharmaceutical formulations including these liposomes and methods of making chelating agent liposomes. Because the chelating agents are loaded in the liposome with high efficiencies, the liposomes are of use in treatment of metal ion overload in subjects. The liposomes can include two or more different chelating agents of different structures and affinities for metal ions.