The present disclosure relates to a targeting guide to be used in the internal fixation for fractured long bones, comprising an arm (11) which is adapted and configured to be connected to an implant (13) which is adapted and configured to be inserted into a fractured long bone (15), a first guide member (17) and a second guide member (15) being arranged one inside the other and being displaceable with respect to each other in a displacement direction between a release configuration and a locking configuration, one of the guide members (17) being connected to the arm (11) such as to be immobile with respect to the arm (11), a first guide passage (19, 19) formed in the first guide member (17) and a second guide passage (27, 27) formed in the second guide member (25), the guide passages (19, 19, 27, 27) being adapted and configured to receive a tool (16) and/or a tool guide (23), wherein in the release configuration the guide passages (19, 27 and 19, 27, respectively) are aligned and define an alignment axis along which the tool (16) or tool guide (23) is freely movable with respect to the guide members (17, 25), and wherein in the locking configuration the guide passages (19, 27 and 19, 27, respectively) are misaligned and/or offset such as to clamp the tool (16) or tool guide (23) received in the guide passages (19, 19, 27, 27), and an actuation mechanism adapted and configured to displace the guide members (17, 25) with respect to each other between the release configuration and the locking configuration.
