Jian Lin,Anna Ericsson,Ann-Marie Campbell,Gary Gustafson,Zhongguo Wang,R. Bruce Diebold,Susan Ashwell,David R. Lancia, JR.,Justin Andrew Caravella,Wei Lu
申请号：
US15677748
公开号：
US20180086733A1
申请日:
2017.08.15
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula:where A, B, U, V, Z, W1, W2, W3, and R1-R6 are described herein.
