The present invention provides a control apparatus for use in dispensing machines which can easily set up a plural kinds or a plural numbers of dispensing machines in the same manner. To do this end, the control apparatus for dispensing machines operates and controls a plural kinds or a plural numbers of dispensing machines in accordance with a prescription data. Use conditions of each dispensing machines are stored in an use condition setting file. A dispensing machine to be used for dispensing is selected in accordance with both the prescription data and the use condition setting file.