KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
发明人:
Lee Woo-Song,Ryu Young-Bae,Kim Young-Min,Park Su-Jin,Rho Mun-Chual,Jeong Hyung-Jae,Kwon Hyung-Jun
申请号:
US201214126106
公开号:
US10136663(B2)
申请日:
2012.06.13
申请国别(地区):
美国
年份:
2018
代理人:
Womble Bond Dickinson (US) LLP `Penny John J.
摘要:
The present invention relates to a complex comprising a compound of formula (I), or a plant extract comprising the compound or a fraction thereof; and stevioside, or a plant extract comprising the stevioside or a fraction thereof, and relates to a pharmaceutical composition for preventing or treating an influenza virus infection comprising the complex as an active ingredient. Also, the present invention relates to a food composition for preventing or improving an influenza virus infection, a virucidal quasi-drug composition, a virucidal feed additive, and a feed, which comprises the complex as an active ingredient. According to the present invention, the complex comprising a compound of formula (I), or a plant extract comprising the compound or a fraction thereof; and stevioside, or a plant extract comprising the stevioside or a fraction thereof exhibits a virucidal effect and an effect of inhibiting cell degradation against an influenza virus as well as antiviral efficacy in a specific pathogen-free (SPF) ch