Bioceramic based nanofaciliated strategic targeted drug delivery system of bisphosphonate for osteoporosis

• 收藏
• 分享

专利权人:

发明人:

TALEGAONKAR SUSHAMA,NEGI PURNIMA,VOHORA DIVYA,AHMAD FARHAN JALEES,GUPTA SARIKA

申请号：

IN1516/DEL/2014

公开号：

IN2014DE01516A

申请日:

2014.06.06

申请国别(地区):

IN

年份:

2015

代理人:

摘要：

The present invention provides a bioceramic based polymer nanoconjugates of bisphosphonate for treatment of osteoporosis. Nano-conjugates composition for regulated release of antiresorptive agent comprising of bioceramic in aqueous phase and also containing respective PLGA and mPEG in organic phase wherein: - The ratio of PLGA to PEG may range from 1:1 to 5:2. The ratio of bisphosphonate and hydroxy apatite range from 1:1 to 4:1 - The size of nanoconjugates varies from 50nm to 500nm. - The entrapment efficiency may be in the range of 50 ± 2.5% to 93 ± 3.0%

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/