A ventilator system and method for medical use includes an integrated blower. The ventilator system may include an inspiration port for connection to an inspiratory limb of a dual-limb patient circuit, and an expiration port for connection to an expiratory limb of the dual-limb patient circuit. The system also includes a gas delivery device connected to the inspiration port to supply a pressurized flow of gas to the inspiration port to generate a positive pressure, and a blower having an inlet that is operatively connected to the expiration port and configured to be controlled to selectively supply a negative pressure level between 4 and 120 cmH2O to the expiration port. The system also includes an outlet to exhaust gas received from the expiration port. In another embodiment, the ventilator system includes a blower to generate positive pressure/flow to augment flow for noninvasive ventilation.