Garvey, David S.,Larosa, Gregory J.,Greenwood, Jeremy R.,Frye, Leah L.,Quach, Tan,Cote, Jamie B.,Berman, Judd
申请号:
AU2012325341
公开号:
AU2012325341B2
申请日:
2012.10.19
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Compounds are disclosed that are useful for treating ophthalmic conditions caused by or related to production of toxic visual cycle products that accumulate in the eye, such as dry adult macular degeneration, as well as conditions caused by or related to the misfolding of mutant opsin proteins and/or the mis-localization of opsin proteins. Compositions of these compounds alone or in combination with other therapeutic agents are also described, along with therapeutic methods of using such compounds and/or compositions. Methods of synthesizing such agents are also disclosed.