Pyridin-2(1h)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

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专利权人:

FORMA THERAPEUTICS INC.

发明人:

Ashwell, Susan,Campbell, Ann-Marie,Caravella, Justin Andrew,Diebold, R. Bruce,Ericsson, Anna,Gustafson, Gary,Lancia, Jr.,Lin, Jian,Lu, Wei,Wang, Zhongguo

申请号：

NZ73037315

公开号：

NZ730373A

申请日:

2015.09.18

申请国别(地区):

NZ

年份:

2019

代理人:

摘要：

The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: (I) where A, U, W1, W2, W3, R1-R6, and R9 are described herein.

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